October 17, 2006

New Diabetes Drug

This might be of interest to my fellow diabetics.

Diabetics gained a new way of controlling their blood sugar levels Tuesday with federal approval of a novel pill for Type 2 diabetes, which affects about 20 million Americans.

The Food and Drug Administration said it approved Januvia, which enhances the body's own ability to lower blood sugar levels, after clinical trials showing the new pill works just as well as older diabetes drugs, but with fewer side effects like weight gain. The drug is made by Merck and Co. Inc.

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Januvia, also known as sitagliptin phosphate, works with a one-two punch: It increases levels of a hormone that triggers the pancreas to produce more insulin to process blood sugar while simultaneously signaling the liver to quit making glucose. The pill does that by blocking production of an enzyme, called DPP-4, that normally inactivates that hormone.

Unfortunately, this drug may be out of reach for many Americans -- rather than the current $15.00 to $30.00 a month cost for the most common generic diabetes drugs, this one will cost nearly $150.00. Whether and when insurance companies will cover the medication and at what price level is unknown at this time.

Novartis is expecting approval of a similar medication by year's end.

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